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目的分析经电子支气管镜介入治疗复治肺结核空洞的临床疗效。方法治疗组采用内科化疗+结核空洞局部灌注抗结核药物凝胶介入治疗,对照组单纯采用内科规范抗痨化疗,均完成21个月治疗疗程。结果治疗组治疗21个月后痰菌阴转率89.5%,病灶治疗有效率94.7%,空洞治疗有效率92.1%,明显高于对照组71.3%,66.3%,62.5%(P<0.05),治疗组未发现与介入治疗有关的严重不良反应。结论经电子支气管镜介导下肺结核空洞局部灌注抗结核药物凝胶配合内科化疗,具有安全,并发症少,病人易接受等优点,胸片显示空洞闭合率高、病灶吸收快。
Objective To analyze the clinical efficacy of electronic bronchoscopic interventional treatment of pulmonary tuberculosis. Methods The patients in the treatment group were treated with medical chemotherapy plus tuberculous local perfusion of antitubercular drug gel, while those in the control group were only treated with medical standard anti-tuberculosis chemotherapy. All of them completed 21 months of treatment. Results After 21 months of treatment, the sputum negative conversion rate was 89.5%, the effective rate of focal treatment was 94.7% and the emptying effective rate was 92.1%, which was significantly higher than that of the control group (71.3%, 66.3%, 62.5%, P <0.05) The group found no serious adverse reactions associated with intervention. Conclusions Electron bronchoscopic pneumonectomy pulmonary vaso-perfusion anti-TB drug gels with medical chemotherapy, with safety, fewer complications, the patient easy to accept the advantages of chest X-ray showed high rate of closed cavity, the lesion absorption fast.