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本文对福州市鼓楼区、台江区1983～1984两年内发现的85例先天畸形儿进行致畸危险因素病例对照调查。结果发现,先天畸形与患儿母亲妊娠前后患病、用药及化学暴露史有明显的联系,与父亲化学暴露史、父母双方物理暴露因素、吸烟、饮酒、家族慢性病史及近亲婚配无明显的联系。上述发现的危险因素值得今后深入研究,并可提供优生学保健指导参考。
In this paper, 85 cases of congenital malformations found in Gulou District and Taijiang District from 1983 to 1984 were investigated by case-control study. The results showed that congenital malformations and mothers before and after pregnancy, illness and medication and history of chemical exposure were significantly linked with the father of chemical exposure history, physical exposure to both parents, smoking, alcohol consumption, family history of chronic disease and the relationship between marriage and no significant relationship . The above-mentioned risk factors deserve further study, and can provide eugenic health guidance.