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本文采用开放试验评价了静注米力农对冠心病病人的血流动力学、代谢和神经激素效应以及抗心肌缺血效果。 20例经冠脉造影证实的稳定型心绞痛冠心病患者,研究前停用心脏活性药物至少3~7天。在行对照踏车运动试验后,先在10分钟内静注负荷量(50μg/kg)的米力农,然后以每分钟0.5μg/kg静滴,直至第二次踏车运动后10分钟。结果静注米力农时的运动平均动脉
In this paper, an open trial was conducted to evaluate the hemodynamic, metabolic and neurohormonal effects and anti-ischemic effects of intravenous infusion of Milrinone in patients with coronary heart disease. Twenty patients with stable angina pectoris confirmed by coronary angiography were stopped using cardiac active drugs for at least 3-7 days prior to the study. After a treadmill exercise test, the first dose of milrinone (50 μg / kg) was intravenously administered within 10 minutes and then intravenously at 0.5 μg / kg per minute until 10 minutes after the second treadmill exercise. Results The average arterial mean arterial pressure at Milrinone injection