论文部分内容阅读
Bone morphogenetic protein-7 is widely Accepted as an inducer for bone marrow stem cells differ-entiating into osteoblasts and chondrocytes.Whether bone marrow stromal cells differentiate into neuron-like cells remains unclear.The current study examined the presence of positive cells for in-termediate filament protein and microtubule associated protein-2 in the cytoplasm of bone marrow stromal cells induced by bone morphogenetic protein-7 under an inverted microscope, while no expression of glial fibrillary acidic protein was found.Reverse transcription PCR electrophoresis also revealed a positive target band for intermediate filament protein and microtubule-associated protein 2 mRNA.These results confirmed that bone morphogenetic protein-7 induces rat bone marrow stromal cells differentiating into neuron-like cells.