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目的通过对手足口病病例进行病原检测,研究保定市手足口病病原分布情况,为手足口病预防控制提供依据。方法采用荧光RT-PCR法对收集的手足口病病例咽拭子标本进行特异性核酸检测。结果保定市手足口病病原体有肠道病毒71型(Enterovirus 71,EV 71)、柯萨奇病毒A组16型(Coxakivirus A16,Co A16)及其他肠道病毒(other enteroviruses,EV)。发病以4岁以下儿童为主。全年均有病例分布,以5~8月为高峰。样品采集时间以3 d内为好,病毒检出率高。结论引起手足口病的病原以EV7 1病毒、Co A16病毒为主,手足口病防控应以4岁以下儿童为主,在5~8月加强监测和预防控制工作。
Objective To study the pathogen distribution of HFMD in Baoding and to provide a basis for the prevention and control of HFMD. Methods Fluorescent RT-PCR was used to detect the specific nucleic acid in the throat swabs collected from HFMD patients. Results The pathogens of HFMD in Baoding were Enterovirus 71 (EV 71), Coxakivirus A16 (Co A16) and other enteroviruses (EV). The incidence of children under 4 years of age. The distribution of cases all year round is from May to August as the peak. Sample collection time within 3 d is good, the detection rate of the virus is high. Conclusions The pathogens causing HFMD are EV71 virus and Co A16 virus. The prevention and control of hand, foot and mouth disease should be based on children under 4 years of age. Monitoring and prevention and control should be strengthened from May to August.