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目的探讨米非司酮与甲氨碟呤联合治疗子宫切口瘢痕妊娠的临床效果。方法抽取于2008年5月至2012年4月在我院接受保守治疗的子宫切口瘢痕妊娠患者中的73例,所有患者均采用米非司酮与甲氨碟呤联合治疗,观察治疗效果。结果 73例患者均保守治疗成功,其中有24例患者由于血HCG下降不明显而在B超辅助下实施了清宫术,术中未出现大出血,患者在20~45d之内血HCG下降至正常水平,3个月有67例患者月经恢复正常。结论米非司酮与甲氨碟呤联合治疗子宫切口瘢痕妊娠效果显著。
Objective To investigate the clinical efficacy of mifepristone combined with methotrexate in the treatment of uterine incision scar pregnancy. Methods From May 2008 to April 2012 in our hospital received conservative treatment of uterine incision scar pregnancy in 73 patients, all patients were treated with mifepristone and methotrexate, the treatment effect was observed. Results All the 73 patients were conservatively treated. Among them, 24 patients underwent radical mastectomy with B-mode ultrasound due to the insignificant decrease of blood HCG. No major bleeding occurred during operation. The blood HCG level decreased to normal level within 20-45 days Six months later, 67 patients returned to normal menstruation in 3 months. Conclusion The combination of mifepristone and methotrexate treatment of uterine incision scar pregnancy effect significantly.