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1965年美国国家肿瘤机构对水泡状胎块病人在排空时应用予防性化疗进行了有益的研究,其目的是探测水泡状胎块在排空时应用抗肿瘤药物或许能减少或消灭继发的增殖性滋养叶疾病(如局部浸犯或子宫外的播散)。这个研究对100例水泡状胎块患者在排空时静脉给予放线菌素D,此外对另100例水泡状胎块未给药物以作对照,对这200例患者作了总结。结果是:治疗组病人2例发生了增殖性滋养叶疾病,而未遇到1例转移性滋养叶疾病(MTD)。相反,在未治疗组病人有16例发生了增殖性滋养叶疾病,有
In 1965, the National Cancer Institute conducted a useful study on the use of anti-tumor chemotherapy in patients with blister-shaped blisters during emptying, with the aim of detecting that the application of antitumor drugs to blister-shaped blocks during emptying may reduce or eliminate the secondary Proliferative nocturnal disorders (such as topical or extrauterine dissemination). In this study, 100 patients with blister-shaped blocks were given intravenous actinomycin D at emptying, and the other 100 patients with blister-shaped blocks were given no control as a control. The 200 patients were summarized. The result was that two patients in the treatment group had proliferative nocturnal tropic leaf disease without one case of metastatic trophoblastic disease (MTD). In contrast, there were 16 cases of proliferative trophoblastic disease in untreated patients