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目的:观察米非司酮联合益母调经合剂治疗胎盘植入的临床疗效。方法:将40例胎盘植入病例随机分为治疗组和对照组,每组各20例。对照组口服米非司酮治疗,治疗组在对照组治疗基础上加服益母调经合剂。比较治疗前后阴道出血的量与持续时间、胎盘排出时间、血绒毛膜促性腺激素(HCG)降至正常的时间等。结果:总有效率治疗组为95.0%,对照组为60.0%,2组比较,差异有显著性意义(P<0.05)。治疗组72小时时阴道出血量、阴道出血持续时间明显少于对照组,胎盘排出时间、血HCG降至正常时间也均短于对照组,2组比较,差异均有显著性意义(P<0.05)。结论:米非司酮联合益母调经合剂治疗胎盘植入能起到协同作用,加强药效,因而收到很好的疗效。
Objective: To observe the clinical efficacy of mifepristone combined with Yimu Tiaojing Mixture in the treatment of placenta accreta. Methods: Forty cases of placenta accreta were randomly divided into treatment group and control group, with 20 cases in each group. The control group was treated with mifepristone. The treatment group was given Yimu Tiaojing Mixture on the basis of the control group. The amount and duration of vaginal bleeding before and after treatment were compared, the time of placenta excretion and the time of HCG to normal were compared. Results: The total effective rate was 95.0% in the treatment group and 60.0% in the control group. There was significant difference between the two groups (P <0.05). The amount of vaginal bleeding and duration of vaginal bleeding in the treatment group at 72 hours were significantly less than those in the control group, and the time of placental excretion and the blood HCG decreased to normal were also shorter than those in the control group (P <0.05) ). Conclusion: The combination of mifepristone and Yimu Tiaojing Mixture in the treatment of placenta accreta can play a synergistic effect to enhance the efficacy, and thus received a good effect.