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目的探讨黄体剥除联合术后米非司酮预防腹腔镜下保守性手术治疗输卵管妊娠后持续性异位妊娠(per-sistent ectopic pregnancy,PEP)的治疗效果。方法选取50例输卵管妊娠病例,分为2组,观察组28例有生育要求,行腹腔镜下保守手术同时行黄体剥除术,术后口服米非司酮,对照组22例无生育要求,行腹腔镜输卵管切除术。结果二组术后无1例发生PEP,差异无统计学意义(P>0.05),术后血β-HCG恢复到正常的时间差异无统计学意义(P>0.05)。结论黄体剥除联合术后口服米非司酮能成功预防腹腔镜下保守手术治疗输卵管妊娠后PEP的发生,扩大了保守性手术治疗的范围,术后口服药物治疗,减少患者痛苦,且无明显不良反应。
Objective To investigate the efficacy of luteal ablation combined with postoperative mifepristone in preventing laparoscopic conservative surgery for tubal pregnancy after continuous ectopic pregnancy (PEP). Methods Fifty cases of tubal pregnancy were selected and divided into two groups. In the observation group, 28 cases had fertility requirements. Laparoscopic conservative surgery was performed simultaneously with luteal debridement. Oral mifepristone was administered after operation. In the control group, 22 cases had no requirement of reproduction, Laparoscopic tubal resection. Results No postoperative PEP was found in the two groups. There was no significant difference in PEP between the two groups (P> 0.05). There was no significant difference in postoperative blood β-HCG recovery to normal time (P> 0.05). Conclusion Luteal removal combined with postoperative oral mifepristone can successfully prevent laparoscopic conservative surgery in the occurrence of tubal pregnancy after PEP, expanding the scope of conservative surgery, postoperative oral medication, reduce patient pain, and no significant Adverse reactions.