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血管紧张素 转换酶 (ACE)是肾素 -血管紧张素 (RAS)系统的关键酶 ,其在高血压发病中的作用已得到了肯定。近年来发现在人 ACE基因的第 16内含子 2 87bp长度片段的缺失或插入基因多态性与高血压关系密切 ,是高血压的候选基因之一〔1〕。由于 2型糖尿病、心血管疾病和高血压病常
Angiotensin converting enzyme (ACE) is a key enzyme in the renin-angiotensin system (RAS) and its role in the pathogenesis of hypertension has been affirmed. In recent years, it has been found that the deletion or insertion gene polymorphism of the 2 87 bp fragment of the 16th intron of human ACE gene is closely related to hypertension and is one of the candidate genes for hypertension [1]. Because of type 2 diabetes, cardiovascular disease and hypertension often