目前对宿主防御系统抗阿米巴感染的机制还没有完全弄清。但可以肯定,宿主的遗传因素可以影响这种机制。本文研究巨噬细胞对小鼠肠阿米巴病的作用。给实验动物二氧化硅颗粒可以特异地破坏巨噬细胞,而保留淋巴细胞和多形核细胞的功能。通过这种处理可以降低宿主以巨噬细胞为主要效应细胞在感染中的抵抗力。 The mechanism of the host defense system against amoeba infection is not yet fully understood. But to be sure, the host’s genetic factors can affect this mechanism. This article studies the role of macrophages in murine intestinal amoebiasis. To experimental animals, silica particles can specifically destroy macrophages while retaining the functions of lymphocytes and polymorphonuclear cells. By this treatment, it is possible to reduce the host’s resistance to infection by macrophages as the predominant effector cells.