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目的调查广州地区男男性行为者(MSM)梅毒、艾滋病病毒(HIV)感染现况,并分析感染梅毒的危险因素。方法将各类场所或通过网络募集的MSM转介到广州市皮肤病防治所VCT门诊,知情同意后,通过结构式问卷,收集调查对象的人口学特征及与梅毒感染可能相关的因素,采集血清检测梅毒和HIV抗体,SPSS 13.0分析资料。结果共募集MSM 1156人,梅毒和HIV总计感染率为10.98%,梅毒感染率为5.5%,HIV感染率为7.6%,梅毒和HIV合并感染率为2.16%。不同职业、场所、籍贯的MSM梅毒感染率差异无统计学意义(P>0.05)。自由职业、工人、商业服务业MSM的HIV感染位居前三位,非广州户籍MSM的HIV感染率高于广州籍;HIV阳性者感染梅毒风险较对照组高7.7倍。多因素分析表明:非固定性伴肛交[比值比(OR)=2.15,95%可信区间(CI):1.02~4.54]、HIV阳性(OR=7.68,95%CI:3.94~14.97)、对自己感染梅毒高风险的认知(OR=3.50,95%CI:1.22~10.08),是MSM感染梅毒的危险因素。结论广州地区MSM梅毒现症感染率低于HIV感染率,但梅毒血清螺旋体明胶颗粒凝集实验阳性率高于HIV阳性率,梅毒感染相关的因素是多方面的,需要结合当地实际开展梅毒和HIV的防治工作。
Objective To investigate the status of syphilis and HIV infection among men who have sex with men (MSM) in Guangzhou and to analyze the risk factors of syphilis infection. Methods All kinds of venues or MSMs recruited through Internet were referred to VCT clinic of Guangzhou dermatology prevention and treatment center. After obtaining informed consent, demographic characteristics of the survey subjects and possible factors related to syphilis infection were collected through structured questionnaires, and serum samples were collected Syphilis and HIV antibodies, SPSS 13.0 analysis data. Results A total of 1156 MSM were recruited. The total syphilis and HIV infection rates were 10.98%, syphilis infection rate 5.5%, HIV infection rate 7.6% and syphilis and HIV infection rate 2.16%. There was no significant difference in MSM syphilis infection rates among different occupations, places and native places (P> 0.05). HIV infection among MSM in freelance, workers and commercial service ranks the top three, HIV prevalence in non-Guangzhou MSM is higher than that in Guangzhou; HIV-positive people have 7.7 times more risk of syphilis infection than control group. Multivariate analysis showed that the odds ratio was (OR = 2.15, 95% CI: 1.02-4.54), HIV positive (OR = 7.68, 95% CI: 3.94-14.97) Cognition of high risk of contracting syphilis (OR = 3.50, 95% CI: 1.22 to 10.08) was a risk factor for MSM infection with syphilis. Conclusions The prevalence of syphilis infection in MSM in Guangzhou is lower than that of HIV infection, but the positive rate of serogroup gelatin particle agglutination in syphilis is higher than that of HIV. The factors related to syphilis infection are many and need to be combined with the actual local syphilis and HIV Prevention and control work.