【摘 要】
：
通过5-氨基-4-氰基-1-苯基吡唑与甲酸发生环合、再经氯化和芳香族亲核取代反应,合成了12种新的含1,3,4-噻二唑环吡唑并[3,4-d]嘧啶类化合物.目标化合物的结构经红外光谱、核
【机 构】
：
湖北民族学院生物资源保护与利用湖北省重点实验室,湖北民族学院化学与环境工程学院,
论文部分内容阅读
通过5-氨基-4-氰基-1-苯基吡唑与甲酸发生环合、再经氯化和芳香族亲核取代反应,合成了12种新的含1,3,4-噻二唑环吡唑并[3,4-d]嘧啶类化合物.目标化合物的结构经红外光谱、核磁共振氢谱、质谱和元素分析方法予以确认.初步的生物活性测定试验表明,在50 mg/L浓度下,大部分目标化合物对小麦纹枯病菌(Rhizoctonia cerealis)表现出较好的杀菌活性,其中化合物5b,5d和5j的抑菌率超过90%.
Through the ring-closure of 5-amino-4-cyano-1-phenylpyrazole with formic acid and subsequent chlorination and aromatic nucleophilic substitution reactions, 12 new 1,3,4-thiadiazoles Cyclopyrazolo [3,4-d] pyrimidines were synthesized.The structures of target compounds were confirmed by IR, 1HNMR, MS and elemental analysis.A preliminary bioassay assay showed that under the concentration of 50 mg / L , Most of the target compounds showed good bactericidal activity against Rhizoctonia cerealis, and the inhibitory rates of compounds 5b, 5d and 5j exceeded 90%.
其他文献
Objective To evaluate the safety and effectiveness of direct gastroscopy for detecting gastric cancer.Methods Clinical screening by direct gastroscopy was per
Quantifying trends in soil microbial biomass carbon (SMBC) under contrasting management conditions is important in understanding the dynamics of soil organic ma
With the rapid development of the Internet, multi documents summarization is becoming a very hot research topic. In order to generate a summarization that can e
Based on the investigation and analysis of characteristics of precipitation, natural environment, socio-economic factors and soil erosion, this paper indicates
提出一种适用于宽电压范围的H桥三端口变换器.在H桥升降压变换器的基础上引入变压器副边整流滤波电路,形成变换器的第3个输出端口,从而构造出H桥三端口变换器；变换器包括两个
针对在瑞利衰落信道下正交幅度调制(QAM)信号识别难的问题,利用多天线空间分集可以提高接收信号信噪比的特点,提出了一种基于多天线接收分集技术的识别方法.首先给出等增益分
To study the structure of microbial communities in the biological hydrogen production reactor and determine the ecological function of hydrogen producing bacter
介绍了Z箍缩初级实验平台激光触发系统的设计和单路样机验证实验结果.采用12台激光器、24个激光触发主开关来实现24路电流脉冲的精确同步,由Nd:YAG四倍频脉冲激光来触发开关,
系统研究了1,4,7-三(2-羟基丙基)-1,4,7-三氮环壬烷(L1)和1,2-双[N,N’-二(2-羟基丙基)-1,4,7-三氮杂环壬基]乙烷(L2)铜配合物([CuL1](ClO4)(NO3)和[Cu2L2](ClO4)4])以及锌配
提出一种串联有源电压质量调节器(AVQR)直流侧电压给定值自调整方法。采用可控整流来实现直流侧电压与系统缺损电压相适应的直流侧电压自适应控制,提高了装置的工作效率。以