本文报告 2 6 6 8例食管贲门癌切除术 ,术后发生上消化道出血 2 8例 (1.0 5 % )。其中食管癌切除术 172 8例 ,术后出血 17例 (0 .98% ) ,贲门癌切除术 940例 ,术后出血 11例 (1.17% )。出血最早在术后 3小时 ,最迟 11天。出血量 2 0 0～ 35 0 0ml。出血原因 :吻合口或贲门残胃小弯闭合残端出血为多见 ,主要与吻合技术有关。对贲门癌认为手工吻合优于机械吻合。对于应激性溃疡出血 ,预防性应用H2 受体拮抗剂是减少本病的重要措施。吻合口主动脉瘘 ,是食管贲门癌术后引起致死性出血的严重并发症 ,应以提高吻合技术 ,预防性应用H2 受体拮抗剂、减少食管胃消化性溃疡穿孔 ,是预防吻合口主动脉瘘的关键 This article reports 26,686 cases of esophageal and cardiac resections and 28 cases of upper gastrointestinal bleeding (1.05%). Among them, 172 cases were esophagectomy, 17 cases were postoperative bleeding (0.98%), 940 cases were cardiac resection and 11 cases were postoperative bleeding (1.17%). Bleeding the first 3 hours after the operation, the latest 11 days. Bleeding volume 2 0 0 ~ 35 0 0ml. Bleeding causes: anastomosis or cardia stump small bend closed residual stump bleeding is more common, mainly related to anastomosis. Cardiac cancer that manual alignment better than mechanical anastomosis. For stress ulcer bleeding, prophylactic use of H2 receptor antagonists is an important measure to reduce the disease. Anastomotic aortic fistula is a serious complication of fatal hemorrhage caused by esophageal and cardiac resections. It is necessary to improve the anastomosis technique, prophylactically use H2 receptor antagonist and reduce perforation of peptic ulcer, The key to fistula