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五十年前已有人发现皮质激素可导致肌乏力或肌萎缩。在各种皮质激素中,人工合成的在 C_9位上有氟原子置换的激素如去炎松等导致肌病的可能性尤大。激素引起肌病的个体差异悬殊。从开始用药到出现症状的时间可为数星期到1年以上。出现症状的时间和严重程度与激素的用量亦有关。一般认为每日激素用量超过相当于强的松40mg 时最易出现肌病症状。而在相当于30mg 强的松的范围以内,而又没有
Fifty years ago it was found that corticosteroids can cause muscle weakness or muscle atrophy. In a variety of cortical hormones, the artificial synthesis of fluorine atoms in the C_9 replacement hormone such as triamcinolone and other diseases are particularly likely to cause myopathy. Hormone-induced myopathies vary widely among individuals. The time from the start of medication to the onset of symptoms can range from a few weeks to more than one year. The timing and severity of symptoms are also related to the amount of hormones used. Generally believed that more than the equivalent daily dose of prednisone 40mg when the most prone to myopathy symptoms. And in the equivalent of 30mg prednisone within the range, but not