论文部分内容阅读
目的:评价还原型谷胱甘肽与前列地尔对慢性肾衰竭(CRF)患者肾功能的改善及生活质量的影响。方法:选取2015年8月—2016年10月间收治的CRF患者86例,采用随机数字表法将其分为对照组和观察组,每组43例;对照组患者给予常规方法治疗,观察组患者给予还原型谷胱甘肽与前列地尔治疗;比较治疗前后两组患者肾功能各指标(Cr、BUN、CCr测得值)的改善情况及生活质量评分值的变化。结果:治疗后观察组患者肾功能各项指标测得值优于对照组(P<0.05),生活质量各方面的评分值高于对照组(P<0.05)。结论:采用还原型谷胱甘肽与前列地尔联用治疗CRF患者,能改善其肾功能各指标,提高了患者的生活质量。
AIM: To evaluate the effects of reduced glutathione and alprostadil on renal function and quality of life in patients with chronic renal failure (CRF). Methods: Eighty-six patients with CRF admitted from August 2015 to October 2016 were selected and divided into control group and observation group with 43 cases in each group. Patients in control group were treated by conventional method and observation group Patients were treated with reduced glutathione and alprostadil. Changes of renal function indexes (Cr, BUN and CCr) and changes of quality of life scores were compared between the two groups before and after treatment. Results: After treatment, the indexes of renal function in observation group were better than those in control group (P <0.05), and the scores of quality of life in all aspects were higher than those in control group (P <0.05). Conclusion: The use of reduced glutathione combined with alprostadil in the treatment of CRF patients can improve their renal function indicators, improve the quality of life of patients.