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目的:探究重症妊娠高血压患者通过拉贝洛尔与硫酸镁治疗后其治疗效果及对分娩结局产生的影响。方法:选取2014年1月至2017年1月南阳市张仲景医院收治的重症妊娠高血压患者80例,依随机分组标准分为观察组(40例)和对照组(40例)。对照组患者治疗方法为硫酸镁治疗,观察组治疗方法为硫酸镁联合拉贝洛尔治疗。从血压改善、分娩结局、不良反应发生及生存质量状况4方面入手,针对相关内容进行分析。结果:观察组患者血压改善情况明显优于对照组(P<0.05);在分娩结局方面,观察组早产、新生儿窒息、胎儿窘迫及巨大儿发生率明显低于对照组(P<0.05);观察组不良反应发生率为7.5%,与对照组的5%比较,差异无统计学意义(P>0.05);在生存质量方面,观察组患者各项指标得分均比对照组高(P<0.05)。结论:重症妊娠高血压患者通过拉贝洛尔与硫酸镁治疗后,在改善患者血压水平及分娩结局的同时,使患者生存质量显著提高,且不良反应发生率较低。
Objective: To investigate the effects of labetalol and magnesium sulfate on the treatment outcome and delivery outcome of severe pregnancy-induced hypertension. Methods: From January 2014 to January 2017, 80 cases of severe pregnancy-induced hypertension admitted in Zhang Zhongjing Hospital of Nanyang City were selected and randomly divided into observation group (40 cases) and control group (40 cases). Control group patients with magnesium sulfate treatment, the observation group treatment with magnesium sulfate and labetalol treatment. From the aspects of blood pressure improvement, delivery outcome, occurrence of adverse reactions and quality of life status, the paper analyzes the relevant contents. Results: The improvement of blood pressure in the observation group was significantly better than that in the control group (P <0.05). The incidence of premature delivery, neonatal asphyxia, fetal distress and macrosomia in observation group were significantly lower than those in control group (P <0.05). The incidence of adverse reactions in the observation group was 7.5%, which was not significantly different from that in the control group (P> 0.05), while in the quality of life, the score of each index in the observation group was higher than that in the control group (P <0.05 ). Conclusion: After treatment with labetalol and magnesium sulfate in patients with severe pregnancy-induced hypertension, the patients’ quality of life is significantly improved and the incidence of adverse reactions is lower while improving their blood pressure and delivery outcomes.