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目的分析非酮症性高血糖偏侧舞蹈症患者脑部CT及MRI影像学特点。方法回顾性分析11例经临床确诊的非酮症性高血糖偏身舞蹈症患者的脑部CT及MRI表现。11例患者均接受至少一次CT及MRI平扫,其中2例行MRI增强检查,4例加做DWI序列,6例加做MRS序列,2例加做DTI序列,3例复查MRI平扫,1例复查CT平扫。结果 9例CT见豆状核和/或尾状核头部片状高密度影,2例CT阴性;T_1WI 9例高信号,2例阴性;DWI 2例高低混杂信号,1例低信号,1例阴性;MRS检查:NAA峰6例均降低,Cho峰6例均升高,NAA/Cr比值6例均降低,Cho/Cr比值6例均升高;DTI 1例显示左侧内囊前肢纤维束受损,FA值减低,1例阴性。结论非酮症性高血糖偏侧舞蹈症脑部CT及MRI均具有特征性影像表现,DWI、MRS及DTI等序列对确定病变性质、评估神经元丢失或损伤、纤维束受损等有价值。
Objective To analyze the CT and MRI features of brain in patients with non-ketotic hyperglycemic chorea. Methods The brain CT and MRI findings of 11 patients with clinically diagnosed nonketotic hypercholesterolemic chorea were retrospectively analyzed. All the 11 patients underwent CT and MRI plain scan. Among them, 2 patients underwent MRI enhanced examination, 4 patients underwent DWI, 6 patients underwent MRS, 2 patients underwent DTI, 3 underwent MR plain scan, 1 Case review CT scan. Results 9 cases of CT showed lamellar nucleus and / or caudate nucleus high density, 2 cases of CT negative; T_1WI 9 cases of high signal, 2 cases negative; DWI 2 cases of mixed signal, 1 case of low signal, 1 6 cases with NAA / Cr ratio decreased, and Cho / Cr ratio increased in 6 cases. In DTI, 1 case showed that left forelimb of left internal capsule Beam damage, FA value decreased, 1 case negative. Conclusions CT and MRI of nonketotic hyperchumbranous chorea are characterized by characteristic images. The sequences of DWI, MRS and DTI are valuable in determining the nature of lesions, evaluating the loss or damage of neurons, and the damage of fiber bundles.