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在住院患儿615例新生儿中,发生医院感染性眼炎43例。对眼分泌物细菌培养,均培养出病原菌。多数病原菌为条件性致病菌,其中铜绿假单胞菌16例、肺炎克雷伯氏菌9例、大肠埃希氏菌6例、鼻硬结克雷伯氏菌4例等。多数菌株对青霉素、氨苄青霉素、麦迪霉素显示耐药;而对氨基糖甙类抗生素:卡那霉素、丁胺卡那、庆大霉素均敏感。对于眼炎的治疗,临床采用诺夫沙星眼药或按药敏结果,用对病原菌敏感的抗生素配制眼药液点眼,取得良好效果。
Among 615 newborns with hospitalized children, 43 cases of hospital-acquired ophthalmia occurred. Eye secretions bacterial culture, are cultivated pathogenic bacteria. Most pathogens are opportunistic pathogens, including 16 cases of Pseudomonas aeruginosa, 9 cases of Klebsiella pneumoniae, 6 cases of Escherichia coli, 4 cases of Klebsiella pneumoniae and so on. Most strains of penicillin, ampicillin, midecamycin showed resistance; and aminoglycoside antibiotics: kanamycin, amikacin, gentamicin are sensitive. For the treatment of ophthalmia, the clinical use of novetsulfan eyedrops or drug susceptibility results, with the pathogen sensitive antibiotic eye drops preparation, and achieved good results.