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目的 探讨双侧乳腺癌临床诊断与治疗的有关问题,提高乳腺癌的生存率.方法 回顾分析28例双侧乳癌的临床资料.28例中有7例第二侧为转移性癌,其中4例放弃手术而死亡,24例第二侧癌经手术治疗,并辅以化疗、放疗等综合治疗,术后2年、3年、5年和10年生存率分别为92.8%、82.1%、53.6%和21.4%,与同期总的乳腺癌5年生存率相差无几.第二侧癌发生的最短时间距第一侧癌术后7个月,最长时间为14年.第一侧癌平均发病年龄为45岁,第二侧癌为49岁.第一、第二侧乳癌均以T2占大多数,T1仅1例次,T3为12例次,T4没有.病理类型以浸润性导管癌最多,其次为单纯癌.结论 双侧乳腺癌的生存率与总体乳腺癌的生存率相差无几,一旦发现应该积极处理,只要处理得当,预后还是相当好的.
Objective To investigate the clinical diagnosis and treatment of bilateral breast cancer and improve the survival rate of breast cancer. Methods The clinical data of 28 cases of bilateral breast cancer were retrospectively analyzed. Of the 28 cases, 7 cases had metastatic cancer on the second side, including 4 cases. After giving up surgery and dying, 24 patients with second side cancer were treated with surgery and supplemented with chemotherapy, radiotherapy, etc. The postoperative 2-, 3-, 5-, and 10-year survival rates were 92.8%, 82.1%, and 53.6%, respectively. And 21.4%, with the same period of the total 5-year survival rate of breast cancer is almost the same. The second side of the cancer occurred from the shortest time from the first side of the cancer after surgery 7 months, the longest time is 14 years. The first side of the average age of cancer Forty-five years old, the second side of the cancer was 49 years old. The first and second side of the breast cancer were mostly T2, T1 was only 1 case, T3 was 12 times, T4 was not. The most pathological type was invasive ductal carcinoma. Followed by simple cancer. Conclusions The survival rate of bilateral breast cancer is almost the same as the overall survival rate of breast cancer. Once it is found that it should be actively dealt with, as long as it is handled properly, the prognosis is still quite good.