用生物杀虫剂茶蚕颗粒体病毒接种中国仓鼠肺细胞（ＣＨＬ）和鸡胚细胞未能引起细胞病变，茶蚕颗粒病毒亦不能在其中增殖，接种病毒颗粒后５天的原代细胞和盲代３代的细胞超薄切片的电镜观察未发现病毒包涵体。ＣＨＬ细胞的空斑实验证实了该病毒未感染ＣＨＬ细胞，但进行的ＣＨＬ细胞微核试验出现可疑阳性结果，提示茶蚕颗粒体病毒制剂中某些物质可能会引起遗传物质的改变 Inoculation of Chinese hamster lung cells (CHLs) and chick embryo cells with the biopesticide Tea Silkworm Granulovirus did not cause cytopathic effects, nor did the Tea Silkworm Granulovirus (PCV) proliferate. Primary cells 5 days after inoculation of the virus particles and blind Electron microscopy on the 3rd generation of ultrathin sections of cells revealed no viral inclusions. Plaque experiments in CHL cells confirmed that the virus did not infect CHL cells, but suspicious positive results were observed in the micronucleus test of CHL cells, suggesting that some of the substances in the tea virus may cause genetic changes