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目的研究乳腺浸润性微乳头状癌(IMPC)临床病理特征。方法对44例IMPC组织标本进行组织病理和免疫组化检测,观察其病理改变、淋巴转移情况。结果 IMPC共44例,随访10~65个月,局部复发24例,远处转移8例,死亡12例。44例中有32例淋巴结转移,转移率达72.7%,转移癌灶与原发灶癌巢形态相同。24例脉管淋巴管内见癌栓,侵犯率达54.5%。结论 IMPC具有高度的淋巴结转移,组织学形态及免疫组化相结合可有效诊断。
Objective To study the clinicopathological features of breast invasive papillary carcinoma (IMPC). Methods 44 cases of IMPC tissue samples were histopathologically and immunohistochemically examined to observe the pathological changes and lymphatic metastasis. Results A total of 44 IMPC cases were followed up for 10 to 65 months. There were 24 cases of local recurrence, 8 cases of distant metastasis and 12 cases of death. Among the 44 cases, 32 cases had lymph node metastasis, with a metastasis rate of 72.7%. The metastatic foci had the same morphology as the primary cancerous nests. 24 cases of vascular lymphatic vessels see thrombus, invasion rate of 54.5%. Conclusion IMPC has a high degree of lymph node metastasis, histological morphology and immunohistochemistry can be effectively diagnosed.