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在550例肾移植的患者中,有46例在移植后1～124个月中出现了症状性结核病。所有肾移植患者均使用硫唑嘌呤和强地松龙治疗。供者及受者既往均无结核病史。在肾移植后的随访中对受者进行结核病调查。对结核病患者联合应用扰结核药物治疗。利福平最多应用6个月,异烟肼和乙胺丁醇总共用2年,以后继续用异烟肼预防,剂量依肾功能而定。结果从移植至发现结核病的时间平均为20个月(SD±26.2月)。36例临床诊为结核病,并经细菌学和病理学检查证实。7例胸片检查发现肺结核,有持续发热,仅对抗结核治疗有反应。其余3
Of the 550 renal transplant patients, 46 developed symptomatic TB disease 1 to 124 months after transplantation. All renal transplant patients were treated with azathioprine and prednisolone. Previous donors and recipients had no history of tuberculosis. The recipients were investigated for tuberculosis at follow-up after renal transplantation. TB patients with tuberculosis drug treatment. Rifampicin up to 6 months, isoniazid and ethambutol with a total of 2 years later to continue with isoniazid prophylaxis, dose dependent on renal function may be. Results The average time from transplantation to the detection of tuberculosis was 20 months (SD ± 26.2 months). Thirty-six cases were clinically diagnosed as tuberculosis and confirmed by bacteriological and pathological examination. Seven cases of chest X-ray examination found that tuberculosis, with persistent fever, only anti-TB treatment response. The rest 3