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目的:探讨保守治疗异位妊娠恢复输卵管功能的新方法。方法:对2005年1月～2009年12月该院461例异位妊娠患者采用天花粉蛋白注射液、米非司酮联合自制中药消胚汤治疗,观察血-HCG下降情况及B超监测盆腔包块消失情况。对有生育要求的196例患者待血HCG恢复正常、盆腔包块消失、月经复潮干净后3～5天行输卵管通液术,第2个月行输卵管碘油造影术,观察复通情况。结果:在461例患者中,有426例成功,异位妊娠保守治疗成功率92.4%,有26例输卵管妊娠破裂或流产后行开腹手术,9例用药后血β-HCG下降缓慢放弃保守治疗,行手术治疗。血β-HCG最高25 316 m IU/m l;肝肾功能保守治疗前后无明显改变。结论:联合用药保守方法治疗异位妊娠效果较好,有效保留了妇女的生育功能。
Objective: To explore a new method of conservative treatment of ectopic pregnancy to restore tubal function. Methods: From January 2005 to December 2009, 461 patients with ectopic pregnancy in the hospital were treated with trichosanthin injection and mifepristone combined with homemade Chinese medicine for eliminating embryo decoction. The decrease of blood-HCG and the monitoring of pelvic ultrasonography Block disappears. Of 196 patients with reproductive requirements to be returned to normal blood HCG, pelvic mass disappeared, menstrual tide clean 3 to 5 days after tubal fluid, the first 2 months of tubal lipiodol angiography, observe the situation of the compound. Results: Of the 461 patients, 426 were successful, the conservative treatment success rate of ectopic pregnancy was 92.4%, 26 cases of tubal pregnancy rupture or abdomen laparotomy, and 9 cases of slow blood β-HCG medication to give up conservative treatment Surgical treatment. Blood β-HCG highest 25 316 m IU / m l; liver and kidney function conservative treatment before and after no significant change. Conclusion: The combined treatment of conservative treatment of ectopic pregnancy better, effectively retained the reproductive function of women.