Persistent trigeminal artery (PTA) is a rare abnor-mal vascular anastomosis connecting the intal ca-rotid artery (ICA) with the vertebrobasilar artery. The incidence is 0.1%-0.6% in adult cerebral angiography.1,2 We have recently treated a rare case of post-traumatic PTA-cavemous fistula. In this study, we discussed the mechanisms and treatment of this disease by review-ing literature.