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目的:分析剖宫产术后深静脉血栓患者的血液系统相关指标,探讨其发病的危险因素。方法:以唐山市妇幼保健院2002年1月~2012年3月剖宫产术后2周内发生下肢深静脉血栓(DVT)的57例为病例组,排除研究资料5项以上缺失者2例,最终入选病例组55例。对照组为同年度相同时间段入住该院的未发生DVT的110例剖宫产产妇。收集活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)、凝血酶时间(TT)、纤维蛋白原(Fg)、凝血酶原国际标准化比率(PT-INR)、D-二聚体(D-Dimer)、全血高切黏度、全血中切黏度、全血低切黏度、血浆黏度、红细胞聚集指数等相关化验指标,并对其进行对比研究,对影响DVT的因素进行多因素Logistic逐步回归分析。结果:病例组D-二聚体、全血中切黏度、血浆黏度、红细胞聚集指数均高于对照组,差异均有统计学意义(P<0.05)。结论:D-二聚体是深静脉血栓形成的独立危险因素。
Objective: To analyze the blood system related indexes of patients with deep venous thrombosis after cesarean section and to explore the risk factors of the disease. Methods: Totally 57 cases of deep venous thrombosis (DVT) occurred within 2 weeks after cesarean section in Tangshan Maternal and Child Health Hospital from January 2002 to March 2012 as case group, excluding 2 cases of more than 5 items of study data , The final selected case group of 55 cases. The control group was 110 cesarean section women who did not have DVT during the same period of the same year. The activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time (TT), fibrinogen (Fg), PT-INR, D-dimer (D-Dimer), whole blood high shear viscosity, whole blood shear viscosity, whole blood low shear viscosity, plasma viscosity, erythrocyte aggregation index and other related indicators, and comparative study of the factors affecting DVT by multiple factors Logistic stepwise regression analysis. Results: D-dimer, whole blood shear viscosity, plasma viscosity and erythrocyte aggregation index were higher in the case group than in the control group, with statistical significance (P <0.05). Conclusion: D-dimer is an independent risk factor for deep venous thrombosis.