伴肾综合征出血热在世界许多地区发生;每年在中国40,000—60,000例,南朝鲜和苏联几百例、斯堪的纳维亚和东欧大约100例。最近在日本、南朝鲜和比利时的动物室内发生许多伴肾综合征出血热病例。汉坦以及相关病毒不仅从农村野生啮齿动物中分离到,还从城市野鼠和实验动物鼠中分离到。自1976年以来从未进行过汉坦病毒实验的日本和朝鲜医学中心动物室内的工作人员中,发生了21起伴肾综合征出血热的暴发,患病人数126例,其 Hemorrhagic fever with renal syndrome occurs in many parts of the world; 40,000 to 60,000 cases occur each year in China, hundreds in South Korea and the Soviet Union, and about 100 cases in Scandinavia and Eastern Europe. Recently there have been many cases of hemorrhagic fever with renal syndrome in animal houses in Japan, South Korea and Belgium. Han Tan and related viruses are not only isolated from rural wild rodents, but also from urban wild and laboratory animals. Outbreaks of haemorrhagic fever with renal syndrome occurred in animal laboratories of Japan and North Korea’s medical centers that had never had a Hantaan virus experiment since 1976, with 126 patients affected