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目的:观察鼻咽清毒颗粒和鼻可乐冲洗液合用对鼻咽癌患者放疗后EB病毒壳抗原抗体VCA/IgA滴度水平和鼻咽部症状的影响。方法:将60例鼻咽癌放疗后患者按就诊顺序分成实验组(鼻咽清毒颗粒和鼻可乐冲洗液合用,30例)和对照组(仅用鼻咽清毒颗粒,30例)。结果:治疗后,实验组显效9例、有效10例、无效11例,总有效率为63.33%,VCA/IgA几何平均滴度为20.5;对照组显效3例、有效8例、无效19例,总有效率为36.66%,VCA/IgA几何平均滴度为55.6。2组总有效率、治疗后VCA/IgA几何平均滴度比较均差异有统计学意义(均P<0.05)。2组患者在治疗过程中均无严重并发症和不良反应发生。结论:鼻咽清毒颗粒和鼻可乐冲洗液合用对鼻咽癌患者放疗后EB病毒VCA/IgA滴度水平有明显的抑制作用,对患者鼻咽部症状有较好的改善作用,可能会有助于降低鼻咽癌的发病率。
Objective: To observe the effect of combination of nasopharyngeal purgation granules and nasal cola lotion on VCA / IgA titers and nasopharyngeal symptoms of patients with nasopharyngeal carcinoma after radiotherapy. Methods: Sixty patients with nasopharyngeal carcinoma after radiotherapy were divided into experimental group (n = 30) and control group (nasopharyngeal detoxification particles, n = 30). Results: After treatment, the experimental group was significantly improved in 9 cases, effective in 10 cases and ineffective in 11 cases, with a total effective rate of 63.33%. The geometric mean titer of VCA / IgA was 20.5. In the control group, 3 cases were markedly effective, 8 cases were effective and 19 cases were ineffective. The total effective rate was 36.66%. The geometric mean titer of VCA / IgA was 55.6.2. The geometric mean titer of VCA / IgA after treatment was significantly different (all P <0.05). Two groups of patients in the course of treatment without serious complications and adverse reactions. Conclusion: The combination of nasopharyngeal purgation granules and nasal cola lotion can significantly inhibit the VCA / IgA titer of EBV after radiotherapy in patients with nasopharyngeal carcinoma, and may have a better effect on nasopharyngeal symptoms in patients with nasopharyngeal carcinoma. Helps to reduce the incidence of nasopharyngeal cancer.