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目的：比较微创经皮与切开复位内固定治疗胫骨骨折的临床疗效。方法选择该院胫骨骨折患者46例，随机分成微创组和传统组，每组各23例。根据Johner-Wuhs法对两组手术疗效、术中出血量、切口长度、手术操作时间、骨痂形成时间、术后观察时间进行对比研究。结果微创组与传统组相比较手术出血量少、切口长度短、手术操作时间短骨痂形成时间短、术后观察时间短、手术效果好。差异有统计学意义(P<0.05)。结论微创经皮治疗胫骨骨折具有良好优势，治疗效果满意，值得推广。“,”Objective To compare the clinical efficacy of minimally invasive percutaneous and open reduction and internal fixation for the treatment of tibial fractures. Methods 46 cases of patients with tibial fractures admitted in our hospital in recent 5 years were divided into minimally invasive group and the traditional group, 23 cases in each group. According to Johner-Wuhs method, the clinical efficacy, intraoperative blood loss, incision length, operation time, callus formation time, postoperative observation time of these two groups were compared and studied. Results Compared with the traditional group, the intraoperative blood loss of the minimally invasive group was less, the incision length was shorter, the operation time, callus formation time and postoperative ob-servation time was shorter, and the effect of surgery was better, the differences were statistically significant (P<0.05). Conclusion Minimally invasive percutaneous treatment for tibial fractures has good advantages, and the treatment effect is satisfactory, which is worthy of promotion.