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食管静脉曲张硬化剂注射疗法可分为二类:静脉内注射和静脉周围注射。作者自1977年起作静脉内注射(用5%油酸乙醇胺,每一静脉内注入9～20ml,一次最大剂量为40ml(0.6ml/kg),每周一次,共2～3周,至内窥镜检证实曲张静脉缩小或消失为止。至1983年共施行178例。其中61例在注射后6天至36个月死于肝癌或肝衰,仅1例死于静脉出血。14例进行尸检,男性13例,女性1例,年龄44～74岁。作者对此14例检查食管壁,以观察经过注射硬化剂后食管曲张静脉栓塞后的结果。注射后初期形成血栓,2周后出现肉芽组织逐渐取代血栓,3个月后肉芽组织缓慢机化,9例镜检可见在机化的肉芽组织内有再管化形成,原曲张静脉未见复发,但1例可见新
Esophageal varicose sclerosis injection therapy can be divided into two categories: intravenous injection and intravenous injection. The authors began intravenous injection starting in 1977 with 5-20% oleic-acid ethanolamine, each intravenous injection of 9-20ml, a maximum dose of 40ml (0.6ml / kg), once a week, a total of 2 to 3 weeks, within Speculography confirmed varicose veins narrowed or disappeared so far in 1988. A total of 178 cases were performed in 1983. Of these 61 cases died of liver cancer or liver failure 6 days to 36 months after injection, only 1 died of venous bleed .14 cases were autopsy , 13 males and 1 females aged from 44 to 74. The authors examined the esophageal wall in 14 patients to observe the results of esophageal variceal embolization after injection of sclerosant.At thrombosis occurred at the initial stage after injection and appeared after 2 weeks Granulation tissue gradually replaced thrombus, 3 months after the granulation tissue slowly machine, 9 cases of microscopic examination in the organization of granulation tissue with re-formation, the original varicose veins no recurrence, but in 1 case new