目的观察定量测定血清心肌肌钙蛋白Ⅰ、肌红蛋白在急性心肌梗死诊治中的应用效果。方法选取2013年1月~12月本院收治的82例确诊为急性心肌梗死患者、82例体检健康者为研究对象,并将前者设为观察组,后者设为对照组,检测两组研究对象的血清心肌肌钙蛋白Ⅰ、肌红蛋白水平,并观察观察组在发病后不同时段的血清心肌肌钙蛋白Ⅰ、肌红蛋白水平和急性心肌梗死诊断结果。结果观察组发病后各个时段的血清心肌肌钙蛋白Ⅰ、肌红蛋白水平均高于对照组,且观察组两种检测指标在发作后0~2h、2~4h、3~7d的诊断准确率差异显著,比较差异有统计学意义,P<0.05。结论肌红蛋白早期诊断的准确性更高,即灵敏性更强,但持续时间短于肌钙蛋白Ⅰ,两种指标联合检测可提高诊断正确率。 Objective To observe the effect of serum cardiac troponin I and myoglobin in diagnosis and treatment of acute myocardial infarction. Methods From January 2013 to December 2013, 82 patients diagnosed as AMI in our hospital and 82 healthy subjects were selected as study subjects and the former as observation group and the latter as control group. Two groups of patients The serum levels of cardiac troponin I and myoglobin were observed. The serum levels of cardiac troponin I, myoglobin and acute myocardial infarction were observed in the observation group at different time points. Results The levels of serum cardiac troponin I and myoglobin in observation group were higher than those in control group at each time point after the onset of attack, and the diagnostic accuracy of the two test indexes in observation group at 0 ~ 2h, 2 ~ 4h and 3 ~ 7d after the attack The difference was significant, the difference was statistically significant, P <0.05. Conclusion Myoglobin is more accurate in the early diagnosis, that is more sensitive, but the duration is shorter than that of troponin I. The combined detection of two indexes can improve the diagnostic accuracy.