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作者调查了114例血液病患者发现口腔表征及合并症者共68例(59.6%),其中白血病48例(42.1%),主要临床表征及合并症为牙龈炎,口腔各部位出血,口腔粘膜溃疡,口腔颌面部感染(细菌或霉菌),淋巴结肿大,颌面部蜂窝组织炎,败血症等。文中讨论了口腔表征出现的机理,叙述了治疗方法,特别是对白血病患者因化疗而产生的溃疡进行了探讨。从口腔科的角度配合了血液科的全身化疗工作,提供了早期诊断的指征,并对保障化疗效果具有一定意义。
The authors investigated a total of 68 cases (59.6%) of 114 patients with blood diseases who found oral signs and complications, including 48 cases of leukemia (42.1%). The main clinical manifestations and complications were gingivitis, bleeding in all parts of oral cavity , Oral mucosal ulcer, oral and maxillofacial infection (bacteria or mold), lymphadenopathy, maxillofacial cellulitis, sepsis and the like. This article discusses the mechanism of oral manifestations, describes the treatment methods, especially for patients with leukemia due to chemotherapy-induced ulcers were discussed. The Department of Stomatology from the perspective of the Department of Hematology systemic chemotherapy work, provides an indication of early diagnosis, and to protect the effect of chemotherapy has some significance.