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自然杀伤(NK)细胞约占外周血淋巴细胞的10~15%,是一组不均一的淋巴细胞亚群。它具有非MHC 限制性溶解肿瘤细胞和抗病毒感染的能力,此外NK 细胞还有调节免疫反应及造血功能的作用。随着NK 细胞作用的研究进展,其在器官组织中的分布及其与功能的联系的研究变得越来越重要了。NK 细胞特异性抗体NKH1(CD56)的研制有助于NK 细胞的作用及其表面分子的研究。最近有许多文章报道了人外周血NK 细胞的分布及其不均一性。现认为NK 细胞是
Natural killer (NK) cells account for about 10-15% of peripheral blood lymphocytes and are a heterogeneous group of lymphocytes. It has the ability to lyse non-MHC-restricted tumor cells and antiviral infections, and in addition NK cells regulate the immune response and hematopoietic function. With the research progress of NK cell function, its distribution in organ tissue and its relation with function become more and more important. Development of NK cell-specific antibody NKH1 (CD56) contributes to the role of NK cells and their surface molecules. Recently, many articles have reported the distribution and heterogeneity of NK cells in human peripheral blood. Now that NK cells are