酒精中毒性脑病,又称Wernicke脑病,常由于酒精中毒引起维生素B_1缺乏所致。本病在欧美国家较多见,国内也有报道。病因本病常见的病因为慢性酒精中毒致维生素B_1缺乏。有人报道一组经病理诊断为酒精中毒性脑病的51例中,45例有酒精中毒史,此外,长期偏食、胃肠道疾病以及各种严重的呕吐等,导致维生素B_1的摄入不足或吸收减少,均可发生本病。发病机理慢性酒精中毒时,肝内维生素B_1的储存显著减少,维生素B_1缺乏时,体内的 Alcoholic encephalopathy, also known as Wernicke encephalopathy, often caused by lack of vitamin B 1 due to alcoholism. The disease is more common in Europe and the United States, there are also reports. Cause of the disease common cause of chronic alcoholism caused by vitamin B_1 deficiency. It was reported in a group of pathologically diagnosed as alcoholic encephalopathy in 51 cases, 45 cases of alcoholism, in addition, long-term partial eclipse, gastrointestinal diseases and a variety of serious vomiting, leading to inadequate intake or absorption of vitamin B 1 Reduce, can occur in this disease. Pathogenesis Chronic alcoholism, the liver vitamin B 1 storage was significantly reduced, vitamin B_1 deficiency, the body’s