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目的探讨较低水平β-HCG异位妊娠患者采用腹腔镜保守性治疗对再次受孕的影响。方法 126例较低水平β-HCG异位妊娠患者按照数字表法随机分为两组,观察组63例,对照组63例,观察组采用腹腔镜保守性治疗,对照组采用单纯甲氨蝶呤(MIX)治疗。结果观察组手术均取得成功,术中均保留患者患侧输卵管,无中转开腹手术者。观察组术后β-HCG降至正常的时间为(13.5±4.2)d,月经恢复时间为术后(1.2±0.5)个月,包块消失时间为(5.1±2.7)d;对照组分别为(19.7±6.2)d、(2.5±0.9)个月、(13.8±5.3)d,两组相比,P均<0.05。术后随访6个月。观察组术后输卵管通畅者为54例,受孕者为51例,宫内妊娠者为44例,对照组为40例、29例、23例,两组比较差异均有统计学意义(P<0.05)。结论腹腔镜保守性治疗可以明显提高较低水平β-HCG异位妊娠患者的受孕率。
Objective To investigate the effect of laparoscopic conservative treatment on re-conception in patients with low-level β-HCG ectopic pregnancy. Methods 126 patients with low level of β-HCG ectopic pregnancy were randomly divided into two groups according to the digital table method, 63 cases in the observation group and 63 cases in the control group. The observation group was treated by laparoscopy conservatively and the control group was treated with methotrexate alone (MIX) treatment. Results The operation of the observation group was successful. All the patients retained the affected side of the fallopian tube without intraoperative laparotomy. The time to postoperative β-HCG in the observation group was (13.5 ± 4.2) days, the period of postoperative recovery was 1.2 ± 0.5 months, and the disappearance time of the mass was (5.1 ± 2.7) days. The control group were (19.7 ± 6.2) days, (2.5 ± 0.9) months and (13.8 ± 5.3) days, respectively, both P <0.05. The patients were followed up for 6 months. In the observation group, 54 cases were treated with tubal patency, 51 cases were pregnant, 44 cases were intrauterine pregnancy, 40 cases were in control group, 29 cases were in control group and 23 cases were in control group. The differences between the two groups were statistically significant (P <0.05 ). Conclusion Laparoscopic conservative treatment can significantly improve the pregnancy rate of patients with low level of β-HCG ectopic pregnancy.