论文部分内容阅读
目的探讨糖化血红蛋白(glucosylated hemoglobin,HbAlc)水平在预测妊娠期糖尿病(gestational diabetes mellitus,GDM)孕妇生产结局中的价值。方法将2014年6月至2015年12月在四川省眉山市妇幼保健院进行产前检查并在该院分娩的146例GDM孕妇,按照分娩前HbAlc水平控制情况将其分为控制组86例、未控制组60例,另外选取同期HbAlc水平正常的产妇60例作为对照组,对比分析3组产妇妊娠结局。结果未控制组妊娠期高血压疾病、胎膜早破、羊水过多、剖宫产率、羊水粪染、早产、胎儿宫内窘迫、新生儿窒息和巨大儿发生率明显高于控制组和对照组(P<0.05),控制组和对照组比较差异无统计学意义(P>0.05)。结论 HbAlc水平对GDM孕妇的妊娠结局有较好的预测作用,可将HbAlc水平作为孕妇血糖控制情况的重要监测指标。
Objective To investigate the value of glucosylated hemoglobin (HbAlc) in predicting the outcome of pregnant women with gestational diabetes mellitus (GDM). Methods A total of 146 pregnant women with GDM at our Maternal and Child Health Care Hospital in Meishan City from June 2014 to December 2015 were divided into control group (86 cases) according to the level of HbAlc before delivery. 60 cases of uncontrolled group, another 60 cases of normal pregnant women with the same level of HbAlc at the same period were selected as the control group, and the maternal pregnancy outcomes were compared among the 3 groups. Results The incidence of gestational hypertension, premature rupture of membranes, polyhydramnios, cesarean section rate, meconium-stained amniotic fluid, preterm birth, fetal distress, neonatal asphyxia and giant macrosomia in uncontrolled group were significantly higher than those in control group and control group Group (P <0.05). There was no significant difference between control group and control group (P> 0.05). Conclusions HbA1c level has a good predictive value on the pregnancy outcome of pregnant women with GDM, and HbA1c level can be used as an important monitoring indicator of blood glucose control in pregnant women.