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目的分析晋江市疑似预防接种异常反应(AEFI)的特征,评价监测质量及疫苗接种安全性。方法采用描述性方法对2010—2013年监测资料进行分析。结果晋江市2010—2013年共报告AEFI 155例,报告发生率4.81/10万剂,异常反应发生率0.27/10万剂。所有接种单位均有病例报告,以妇幼保健院报告居多(37.4%);报告时间以3月最多(14.8%),1、2月最少(3.9%);男女比例1.5∶1;年龄集中在3岁以下(72.9%)。一般反应占91.0%,异常反应占5.8%,偶合症占2.6%,心因性反应占0.1%。报告病例数最多的疫苗为百白破、甲流和含麻类疫苗(66.4%);报告发生率前3位分别为白破疫苗、七价肺炎、百白破疫苗。结论晋江市AEFI监测指标均达国家要求,下一步工作重点是端正报告医生态度、加强报告培训范围及完善督导考核。
Objective To analyze the characteristics of suspected anonymous immunization (AEFI) in Jinjiang and evaluate the quality of surveillance and the safety of vaccination. Methods Descriptive methods were used to analyze the monitoring data from 2010 to 2013. Results A total of 155 AEFI cases were reported in Jinjiang from 2010 to 2013, with a reported incidence of 4.81 / 100 000 doses and an abnormal response rate of 0.27 / 10 000 doses. All inoculation units have case reports, most of which are reported by MCH (37.4%); the report period is the highest (14.8%) in March and the least in January and February (3.9%); the male / female ratio is 1.5: 1; the age is concentrated in 3 Aged (72.9%). General reaction accounted for 91.0%, abnormal reaction accounted for 5.8%, coupling accounted for 2.6%, psychogenic reactions accounted for 0.1%. The number of reported cases of the largest number of vaccine for the Dim sum, a stream and containing the ganism vaccine (66.4%); report the incidence of the first three were white broken vaccine, seven price pneumonia, diphtheriae vaccine. Conclusion The AEFI monitoring indicators in Jinjiang City met the national requirements. The focus of the next step was to correctly report the attitude of doctors, strengthen the scope of reporting training and improve the supervision and examination.