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对四数九里香的地上部位进行了化学成分研究。运用硅胶和Sephadex LH-20柱色谱及制备HPLC和TLC等多种分离方法进行分离纯化,共分离得到9个化学成分,通过NMR和MS数据分析,并结合文献对比,鉴定其结构分别为3,3’-[oxybis(methylene)]bis(9-methoxy-9H-carbazole)(1),murrastifoline B(2),murrayaquinone A(3),2,4-二甲氧基苯酚(4),1,2-二甲氧基-4-硝基苯(5),间甲基苯甲醚(6),丁香树脂酚葡萄糖苷(7),β-谷甾醇(8),3-甲氧基-4-羟基反式苯丙烯酸正十八醇酯(9)。化合物4–6和9为首次从九里香属植物中分离得到,化合物2–9为该种植物中首次分离得到。
The chemical composition of four parts of nine parts of the ground was studied. Nine chemical constituents were isolated and purified by silica gel, Sephadex LH-20 column chromatography, preparative HPLC and TLC. Nine chemical constituents were isolated and identified by NMR and MS data analysis. Their structures were identified as 3, 3 ’- [oxybis (methylene)] bis (9-methoxy-9H-carbazole), murrastifoline B (2), murrayaquinone A 2-dimethoxy-4-nitrobenzene (5), m-methylanisole (6), syringaresinol glucoside (7), β-sitosterol - N-octadecyl hydroxycinnamate (9). Compounds 4-6 and 9 were isolated from Grifola for the first time, and compounds 2-9 were isolated from this plant for the first time.