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目的:研究在因黄体功能不全导致先兆流产的治疗中使用黄体酮的临床药效,丰富了临床使用依据。方法:将我院于2014年1月到2015年12月收诊的120例黄体功能不全所致先兆流产的患者任意均分为研究组和对照组,每组60人。本院对研究组和对照组患者采取不同的治疗方式:黄体酮综合治疗和单纯黄体酮治疗。本院观察和记录患者接受治疗后的临床症状和产生的不良反应,通过对比得到研究结果。结果:经过观察和对比,研究组和对照组的总有效率分别为93.33%和71.66%,前者明显大于后者,根据统计学方法计算,其差异值P<0.05,具有统计学意义。每组均有少量患者接受治疗后产生如恶心呕吐、头痛等不良反应症状,比较两组差异值P大于0.05,无统计学意义。结论:治疗因黄体功能不全而导致的先兆性流产,研究组采用的黄体酮综合治疗方法能够带来明显的临床效果,具有非常大的使用价值。
OBJECTIVE: To study the clinical efficacy of progesterone in the treatment of threatened abortion due to corpus luteum insufficiency, which enriched the basis of clinical use. Methods: A total of 120 patients with threatened abortion due to luteal insufficiency in our hospital from January 2014 to December 2015 were randomly divided into study group and control group, with 60 in each group. The hospital for the study group and control group patients take different treatment: progesterone and progesterone treatment alone. The hospital observed and recorded after treatment of patients with clinical symptoms and adverse reactions, obtained by comparing the results of the study. Results: After observation and comparison, the total effective rates of the study group and the control group were 93.33% and 71.66% respectively, the former was obviously higher than the latter. According to the statistical method, the difference was statistically significant (P <0.05). Each group has a small number of patients receiving treatment such as nausea and vomiting, headache and other adverse reactions, compared the difference between the two groups P greater than 0.05, no statistically significant. Conclusion: In the treatment of threatened abortion caused by corpus luteum insufficiency, the progesterone combination therapy adopted by the research group can bring obvious clinical effect and has very great value.