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目的探讨活血化瘀中药不良反应的规律和特点。方法 48例活血化瘀中药不良反应患者,对其临床资料进行回顾性分析。结果不良反应药物中以血栓通的不良反应发生率最高,为35.4%,其次为血塞通,占据22.9%;不良反应累及部位上以皮肤及周边最多,占45.8%,临床上主要表现为皮疹、瘙痒。结论应加强对临床中药制剂的研究监测,掌握患者既往过敏史,明确活血化瘀中药的药理,以降低不良反应的发生率。
Objective To investigate the regularities and characteristics of adverse reactions of traditional Chinese medicine for activating blood circulation and removing blood stasis. Methods Forty - eight patients with adverse reactions of activating blood and removing blood stasis were retrospectively analyzed. Results Adverse reactions of thrombus were the most common adverse reactions, accounting for 35.4%, followed by Xuesaitong, accounting for 22.9%; adverse reactions involving the skin and the periphery of the site up to 45.8%, the main clinical manifestations of rash , Itching. Conclusion It is necessary to strengthen the research and monitoring of clinical Chinese medicine preparations, grasp the history of past allergies and clarify the pharmacology of traditional Chinese medicine in order to reduce the incidence of adverse reactions.