熊去氧胆酸(3α,7β二羟基5β胆烷酸,以下简称ＵＤＣＡ)(1)是中药熊胆的主要成分,曾主要用于治疗胆石疾病[1]。近年来,国外报道了ＵＤＣＡ在治疗各种急性、慢性肝病中的应用[2]。新的研究表明,ＵＤＣＡ不仅对于治疗原发性胆汁性肝硬化、原发性硬化性胆管炎、慢性活动性肝炎具有 Ursodeoxycholic acid (3α, 7β dihydroxy 5β cholanic acid, hereinafter referred to as UDCA) (1) is the main component of the Chinese gall bear bile, which has been mainly used for the treatment of gallstone disease [1]. In recent years, foreign reports of UDCA in the treatment of various acute and chronic liver disease [2]. New research shows that UDCA not only for the treatment of primary biliary cirrhosis, primary sclerosing cholangitis, chronic active hepatitis have