论文部分内容阅读
目的对头孢菌素类与多种西药联合使用所致的不良反应进行分析。方法选取2010年8月-2012年1月在医院使用头孢菌素类药物联合其他药物所致不良反应患者70例,分析患者出现不良反应的原因,及联合使用药物前后不良反应的发生情况。结果联合用药后患者的不良反应发生率明显高于联合用药前,差异有统计学意义(P<0.05);神经系统不良反应最为常见。结论开展头孢菌素类药物与其他药物联用所致不良反应进行分析,对于提高头孢菌素类药物临床应用的有效性和安全性均具有重要意义。
Objective To analyze the adverse reactions caused by cephalosporins combined with various western medicines. Methods Seventy patients with adverse reactions caused by cephalosporins combined with other drugs in the hospital from August 2010 to January 2012 were selected to analyze the causes of adverse reactions and the incidence of adverse reactions before and after the combination of drugs. Results The incidence of adverse reactions in patients after combination therapy was significantly higher than that before combination therapy (P <0.05). Nervous system adverse reactions were the most common. Conclusion The analysis of adverse reactions caused by cephalosporins in combination with other drugs is of great significance for improving the clinical efficacy and safety of cephalosporins.