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近年笔者应用西沙比利治疗慢性习惯性便秘128例,并设对照组进行疗效观察,结果西沙比利疗效显著优于对照组,现报告如下。 1.临床资料 164例均系门诊病人,随机分为治疗组和对照组。治疗组128例,男60例,女68例,年龄52～80岁,平均60岁;对照组36例,其中男16例,女20例,年龄50～78岁,平均58岁。便秘症状持续时间均超过1年,全部病例均经肠镜和/或钡剂灌肠检查,无器质性疾病。排除某些直肠和肛门病变、结肠病变、内分泌系统疾病、药品和化学品、肌力减退、神经系统疾病所致的便秘。按排便次数将其分为轻度(2～3天排便一次)和重度(>5天排便一次)。
In recent years, the author of cisapride treatment of chronic habitual constipation in 128 cases, and the control group for the efficacy of observation, the results of cisapride significantly better than the control group, are as follows. 1. Clinical data 164 outpatients were outpatients were randomly divided into treatment group and control group. The treatment group of 128 patients, 60 males and 68 females, aged 52 to 80 years, mean 60 years; control group of 36 patients, 16 males and 20 females, aged 50 to 78 years, mean 58 years. Duration of constipation symptoms were more than 1 year, all cases were colonoscopy and / or barium enema examination, no organic disease. Excludes certain rectal and anal lesions, colonic lesions, diseases of the endocrine system, medicines and chemicals, muscle weakness, and constipation caused by nervous system disorders. According to the number of defecation will be divided into mild (2 to 3 days defecation time) and severe (> 5 days defecation time).