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目的:探讨米非司酮用于治疗子宫肌瘤的临床疗效。方法:选取我院2005年3月～2011年3月期间确诊为子宫肌瘤的患者500例,给予米非司酮12.5mg/d进行治疗,3个月为1个疗程,500例子宫肌瘤患者米非司酮治疗前后行彩超检查,并进行比较。服药期间监测血常规、肝肾功能,观察药物副反应。结果:应用米非司酮治疗子宫肌瘤患者后,患者子宫和肌瘤的平均体积均比服药治疗前明显缩小,差异有统计学意义(P<0.05)。结论:应用米非司酮治疗子宫肌瘤的临床效果显著,值得临床推广应用。
Objective: To explore the clinical efficacy of mifepristone in the treatment of uterine fibroids. METHODS: A total of 500 patients with uterine fibroids diagnosed in our hospital from March 2005 to March 2011 were selected and treated with 12.5 mg/d mifepristone. Three months were a course of treatment and 500 cases of uterine fibroids. Before and after mifepristone treatment, color ultrasonography was performed and compared. Blood routine, liver and kidney function were monitored during medication, and side effects were observed. Results: After mifepristone treatment of uterine fibroids, the average volume of uterus and fibroids was significantly smaller than before treatment, and the difference was statistically significant (P<0.05). Conclusion: The clinical effect of mifepristone in the treatment of uterine fibroids is significant and worthy of clinical application.