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目的探讨肥胖儿童非酒精性脂肪肝(nonalcoholic fatty liver disease,NAFLD)临床特点及高危因素,为NAFLD的预防和治疗提供帮助。方法分析我院2009年12月-2011年12月收治的106例非酒精性脂肪肝的临床资料,统计其性别、年龄、体重指数(BMI)、空腹胰岛素及甘油三酯结果,并分析体重指数(BMI)、空腹胰岛素及甘油三酯与NAFLD发生的相关关系。结果 106例患儿中,男女发病年龄分布未见统计学差异(P>0.05);体重指数(BMI)及甘油三酯是NAFLD发生的高位因素(P<0.05),而空腹胰岛素水平与NAFLD发生无明显相关关系(P>0.05)。结论 NAFLD多发生于男性患儿;NAFLD的发生受到多种因素影响,但体重指数(BMI)及甘油三酯是主要的相关危险因素。
Objective To investigate the clinical features and risk factors of nonalcoholic fatty liver disease (NAFLD) in obese children, and to provide help for the prevention and treatment of NAFLD. Methods The clinical data of 106 patients with non-alcoholic fatty liver admitted from December 2009 to December 2011 in our hospital were analyzed. Their gender, age, body mass index (BMI), fasting insulin and triglyceride were analyzed. Body mass index (BMI), fasting insulin and triglycerides and NAFLD. Results There was no significant difference in the age distribution of males and females in 106 children (P> 0.05). The body mass index (BMI) and triglycerides were the high risk factors of NAFLD (P <0.05), while the fasting insulin levels and NAFLD No significant correlation (P> 0.05). Conclusions NAFLD frequently occurs in males. The incidence of NAFLD is affected by many factors, but body mass index (BMI) and triglyceride are the major risk factors.