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４３例健康人和１７５例心脏病患者作心－肺运动试验，以评价心功能不全的程度。采用自行车运动递增负荷试验，通过监测每分钟换气量（ＶＥ）、氧摄取量（ＶＯ２）和二氧化碳排出量（ＶＣＯ２）来确定无氧代谢阈值（ＡＴ）。同时也测定峰值ＶＯ２（ＰＶＯ２）和％ＡＴ。ＡＴ［ｍｌ／（ｍｉｎ·ｋｇ）］和ＰＶＯ２［ｍｌ／（ｍｉｎ·ｋｇ）］随年龄增大而下降，男性上述值均高于女性。％ＡＴ值（从年龄和性别预测的ＡＴ值经校正后的ＡＴ百分数）在心功能不全组随ＮＹＨＡ级别增高而降低；心功能Ⅰ、Ⅱ、Ⅲ级分别为８５．３％±１０．３％、７４．７％±１４．１％和５８．８％±１２．８％。１２例间隔３ｈ所测ＡＴ值重复性好（ｒ＝０．８５）。结果表明，心－肺运动试验的指标，特别是ＡＴ可以用作评价心功能不全的客观指标及其心功能不全治疗的效果。
Forty-three healthy subjects and 175 patients with heart disease were tested for heart-lung function to assess the extent of cardiac insufficiency. An anaerobic metabolic threshold (AT) was determined by cycling progressive load test by monitoring VE, oxygen uptake (VO2), and carbon dioxide uptake (VCO2). Peak VO2 (PVO2) and% AT were also determined. AT [ml / (min · kg)] and PVO2 [ml / (min · kg)] decreased with increasing age, and the above-mentioned values were higher in males than in females. % AT values (adjusted AT percentage from age-and-sex-predicted AT values) decreased with increasing NYHA level in patients with cardiac dysfunction; heart function grades I, II, and III were 85.3% ± 10.3% 74.7% ± 14.1% and 58.8% ± 12.8%. The measured AT values of 12 patients at 3h intervals were good (r = 0.85). The results show that the indicators of heart-lung exercise test, especially AT, can be used as an objective index to evaluate cardiac insufficiency and the effect of cardiac dysfunction.