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目的了解莆田市人群麻疹免疫水平,为完善消除麻疹免疫策略提供科学依据。方法用问卷收集调查对象基本信息,采集静脉血2~3mL,用ELISA检测麻疹抗体水平。结果调查抽样的4个镇/街道麻疹抗体几何平均浓度(GMC)为696.5mIU/mL,抗体阳性率90.7%,其中保护性抗体阳性率54.6%;不同年龄组间GMC、抗体阳性率、保护性抗体阳性率均有统计学差异,其中10~14岁、15~24岁组麻疹抗体浓度最低;平原地区麻疹抗体阳性率低于山区和沿海地区;农村抗体阳性率较城镇高。结论应将10~35岁人群作为麻疹防控中关注人群,建议在该人群中开展1剂次麻疹强化免疫;完善预防接种措施,缩小城乡间、不同地区间消除麻疹工作的差异。
Objective To understand the level of measles immunity in Putian and to provide a scientific basis for improving measles immunization strategies. Methods The questionnaire was used to collect the basic information of the surveyed subjects and collect 2-3 mL of venous blood. The level of measles antibody was detected by ELISA. Results The geometric mean concentration (GMC) of measles antibody was 696.5 mIU / mL in 4 towns / streets sampled from the survey, the positive rate of antibody was 90.7%, and the positive rate of protective antibody was 54.6%. The positive rate of GMC, The positive rate of measles antibody in the plains was lower than that in the mountainous area and the coastal area. The positive rate of measles antibody in rural areas was higher than that in the urban areas. Conclusion 10 to 35-year-old population should be concerned about the crowd of measles prevention and control, it is recommended in this population to carry out a dose of measles-intensive immunity; improve the vaccination measures to reduce the differences between urban and rural areas, between different regions to eliminate measles.