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目的:观察研究寿胎四君子汤与黄体酮对早期先兆流产的临床治疗效果。方法:选取我科室2012年11月至2015年1月收治疗的确诊为先兆流产的患者共120例,按随机数字表法分为观察组和对照组各60例,观察组给予寿胎四君子汤治疗,对照组给予黄体酮治疗,随访并记录两组患者的胎儿并发症发生状况、胎儿不良结局状况及两组治疗方案的效果分析。结果:观察组胎儿在Apgar’s评分、胎儿体重、新生儿畸形等方面与对照组相比差异无显著性。观察组在胎膜早破、妊娠期糖尿病、妊娠期高血压、产后出血等分娩期并发症方面仅妊娠期高血压与对照组相比差异有显著性。观察组治疗有效率达90.0%明显高于对照组78.3%。观察组治疗后的血清孕酮值为30.2ng/ml,明显高于对照组25.5ng/ml。结论:寿胎四君子汤早期先兆流产的临床治疗效果确切,值得临床进一步研究和应用。
Objective: To observe the clinical efficacy of Shou Si Si Jun Zi Decoction and progesterone on early threatened abortion. Methods: A total of 120 patients diagnosed as threatened abortion received treatment in our department from November 2012 to January 2015 were randomly divided into observation group (60 cases) and control group (60 cases) according to random number table method. The observation group was given Shoushen Sijunzi Decoction The patients in the control group were given progesterone treatment. The incidence of fetal complications, the status of fetal unhealthy outcome and the treatment effect of the two groups were analyzed. Results: There was no significant difference between the observation group and the control group in Apgar’s score, fetal weight and neonatal malformation. Observation group in premature rupture of membranes, gestational diabetes, gestational hypertension, postpartum hemorrhage and other complications of gestational hypertension only compared with the control group, the difference was significant. Observation group, the effective rate of 90.0% was significantly higher than 78.3% of the control group. The serum progesterone level in the observation group after treatment was 30.2ng / ml, which was significantly higher than that in the control group (25.5ng / ml). Conclusion: The clinical treatment of early fetal threatened abortion of Shou Tai Si Jun Zi Tang is exact and deserves clinical further study and application.