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目的:分析老年中重症心力衰竭的临床内科治疗效果。方法:选取2013年1月至2015年12月期间该院收治的80例中重症心力衰竭老年患者作为研究对象,将其分为对照组和观察组各45,对照组行常规治疗,观察组在对照组基础上加用美托洛尔、厄贝沙坦氢氯噻嗪联合治疗,对比两组患者的临床治疗效果。结果:对照组患者总有效率为80%,观察组患者总有效率为96%,两组患者的疗效比较(χ~2=4.771,P<0.05),治疗后,对照组患者的左室射血分数、B型脑钠肽水平分别为(955.3±101.3)%、(33.6±3.8)pg/ml,观察组患者的左室射血分数、B型脑钠肽水平分别为(783.4±89.7)%、(37.2±4.2)pg/ml,两组患者的的左室射血分数和B型脑钠肽水平比较(T_(左室射血分数)=8.035,T_(B型脑钠肽)=3.963,P<0.05)。结论:美托洛尔、厄贝沙坦氢氯噻嗪联合治疗老年中重症心力衰竭,治疗效果显著,有效的改善了患者的心功能变化,具有重要的应用价值。
Objective: To analyze the clinical medical treatment effect of senile patients with severe heart failure. Methods: A total of 80 elderly patients with severe heart failure admitted to our hospital from January 2013 to December 2015 were selected as study subjects, which were divided into control group and observation group, with 45 cases in each group. The control group received routine treatment. Control group based on the use of metoprolol, irbesartan hydrochlorothiazide combination therapy, the clinical efficacy of the two groups were compared. Results: The total effective rate was 80% in the control group and 96% in the observation group. The curative effect of the two groups was compared (χ ~ 2 = 4.771, P <0.05). After treatment, the left ventricular ejection (955.3 ± 101.3)% and (33.6 ± 3.8) pg / ml respectively. The left ventricular ejection fraction and B-type natriuretic peptide in the observation group were (783.4 ± 89.7) and %, (37.2 ± 4.2) pg / ml respectively. The left ventricular ejection fraction and B-type natriuretic peptide level in two groups were compared (T_ (LV ejection fraction) = 8.035, T_ 3.963, P <0.05). Conclusion: The combination of metoprolol and irbesartan in the treatment of senile patients with severe heart failure has significant therapeutic effect and effectively improves the patients’ cardiac function, which is of great value in application.