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目的探讨鼻内窥镜手术治疗慢性鼻-鼻窦炎的疗效、症状改善及生活质量转归。方法通过前瞻性随机对照设计,对86例慢性鼻-鼻窦炎采用鼻内镜手术治疗,对患者术前、术后1、3、6和12个月主要症状和生存质量状况进行评估,比较患者主要症状和生存质量的变化。结果随访12个月,本组治愈73例(84.9%),好转9例(10.5%),总有效率95.3%;86例实施内镜鼻窦手术治疗的慢性鼻-鼻窦炎患者术后第1、3、6、12个月主要症状的评分呈下降趋势,与术前相比,均明显降低(P<0.01);生理角色、心理健康、情感角色、躯体疼痛、社会功能和总体健康从术后1个月开始逐渐升高(P均<0.05),而生理功能和活力无明显变化,与术前比较差异无统计学意义。与术前比较,20个条目和5大条目从术后1个月开始逐渐下降(P均<0.01)。结论鼻内镜手术对慢性鼻-鼻窦炎患者疗效显著,对患者症状和生活质量改善具有肯定的效果。
Objective To investigate the curative effect, symptom improvement and quality of life of nasal endoscopic sinus surgery for chronic rhinosinusitis. Methods 86 cases of chronic rhinosinusitis were treated by endoscopic sinus surgery through prospective randomized controlled design. The main symptoms and quality of life at 1, 3, 6 and 12 months after surgery were evaluated. The main symptoms and quality of life changes. Results After 12 months of follow-up, 73 cases (84.9%) were cured and 9 cases (10.5%) were cured, with a total effective rate of 95.3%. 86 cases of patients with chronic rhinosinusitis treated by endoscopic sinus surgery had no significant difference The scores of major symptoms at 3, 6, and 12 months showed a decreasing trend, which were significantly lower than those before operation (P <0.01). Physiological role, mental health, emotional role, physical pain, social function and general health 1 month (P <0.05), while no significant changes in physiological function and vitality, compared with the preoperative difference was not statistically significant. Compared with preoperative, 20 items and 5 items decreased gradually from 1 month after operation (all P <0.01). Conclusions Endoscopic surgery has a significant effect on patients with chronic rhinosinusitis and has a positive effect on the improvement of symptoms and quality of life in patients.